mankhwala amadzimadzi ndi mankhwala omwe amakhala ndi ma molecule ambiri (kapena maselo a maselo) omwe ali ndi maatomu ochokera ku chinthu chimodzi chokha chimene chimagwirizanitsidwa ndi mankhwala. Kachilombo kamene kamagwirizanitsidwa ndi chinthu chofanana ndi mankhwala si mankhwala a mankhwala chifukwa chakuti chinthu chimodzi chokha, osati zinthu ziwiri zosiyana, zimakhudzidwa.

Pali mitundu inayi ya mankhwala, malinga ndi momwe ma atomu alili pamodzi:

Mamolekyu amagwirizanitsidwa pamodzi ndi mgwirizano wolimba
magulu a ionic ogwirizanitsidwa pamodzi ndi maubwenzi a ionic
Mitundu yambiri yomwe imagwirizanitsidwa pamodzi ndi zitsulo
maofesi ena omwe amagwirizanitsa pamodzi ndi kukonza mgwirizano wolimba.

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